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A standard calculation methodology for human doubly labeled water studies

dc.contributor.authorSpeakman, John R.
dc.contributor.authorYamada, Yosuke
dc.contributor.authorSagayama, Hiroyuki
dc.contributor.authorBerman, Elena S. F.
dc.contributor.authorAinslie, Philip N.
dc.contributor.authorAndersen, Lene Frost
dc.contributor.authorAnderson, Liam J.
dc.contributor.authorArab, Lenore
dc.contributor.authorBaddou, Issaad
dc.contributor.authorBedu-Addo, Kweku
dc.contributor.authorBlaak, Ellen E.
dc.contributor.authorBlanc, Stéphane
dc.contributor.authorBonomi, Alberto
dc.contributor.authorBouten, Carlijn V. C.
dc.contributor.authorBovet, Pascal
dc.contributor.authorBuchowski, Maciej S.
dc.contributor.authorButte, Nancy F.
dc.contributor.authorCamps, Stefan G. J. A.
dc.contributor.authorClose, Graeme L.
dc.contributor.authorCooper, Jamie A.
dc.contributor.authorCreasy, Seth A.
dc.contributor.authorDas, Sai Krupa
dc.contributor.authorCooper, Richard S.
dc.contributor.authorDugas, Lara R.
dc.contributor.authorEbbeling, Cara B.
dc.contributor.authorEkelund, Ulf
dc.contributor.authorEntringer, Sonja
dc.contributor.authorForrester, Terrence
dc.contributor.authorFudge, Barry W.
dc.contributor.authorGoris, Annelies
dc.contributor.authorGurven, Michael
dc.contributor.authorHambly, Catherine
dc.contributor.authorEl Hamdouchi, Asmaa
dc.contributor.authorHoos, Marije B.
dc.contributor.authorHu, Sumei
dc.contributor.authorJoonas, Noorjehan
dc.contributor.authorJoosen, Annemiek M.
dc.contributor.authorKatzmarzyk, Peter
dc.contributor.authorKempen, Kitty P.
dc.contributor.authorKimura, Misaka
dc.contributor.authorKraus, William E.
dc.contributor.authorKushner, Robert F.
dc.contributor.authorLambert, Estelle V.
dc.contributor.authorLeonard, William R.
dc.contributor.authorLessan, Nader
dc.contributor.authorLudwig, David S.
dc.contributor.authorMartin, Corby K.
dc.contributor.authorMedin, Anine Christine
dc.contributor.authorMeijer, Erwin P.
dc.contributor.authorMorehen, James C.
dc.contributor.authorMorton, James P.
dc.contributor.authorNeuhouser, Marian L.
dc.contributor.authorNicklas, Theresa A.
dc.contributor.authorOjiambo, Robert M.
dc.contributor.authorPietiläinen, Kirsi H.
dc.contributor.authorPitsiladis, Yannis P.
dc.contributor.authorPlange-Rhule, Jacob
dc.contributor.authorPlasqui, Guy
dc.contributor.authorPrentice, Ross L.
dc.contributor.authorRabinovich, Roberto A.
dc.contributor.authorRacette, Susan B.
dc.contributor.authorRaichlen, David A.
dc.contributor.authorRavussin, Eric
dc.contributor.authorReynolds, Rebecca M.
dc.contributor.authorRoberts, Susan B.
dc.contributor.authorSchuit, Jantine
dc.contributor.authorSjödin, Anders
dc.contributor.authorStice, Eric
dc.contributor.authorUrlacher, Samuel S.
dc.contributor.authorValenti, Giulio
dc.contributor.authorVan Etten, Ludo M.
dc.contributor.authorVan Mil, Edgar A.
dc.contributor.authorWells, Jonathan
dc.contributor.authorWilson, George
dc.contributor.authorWood, Brian M.
dc.contributor.authorYanovski, Jack
dc.contributor.authorYoshida, Tsukasa
dc.contributor.authorZhang, Xueying
dc.contributor.authorMurphy-Alford, Alexia J.
dc.contributor.authorLoechl, Cornelia U.
dc.contributor.authorMelanson, Edward L.
dc.contributor.authorLuke, Amy
dc.contributor.authorPontzer, Herman
dc.contributor.authorRood, Jennifer C.
dc.contributor.authorSchoeller, Dale A.
dc.contributor.authorWesterterp, Klaas R.
dc.contributor.authorWong, William W.
dc.date.accessioned2021-10-20T10:44:52Z
dc.date.available2021-10-20T10:44:52Z
dc.date.created2021-06-07T11:58:15Z
dc.date.issued2021
dc.identifier.citationSpeakman, J. R., Yamada, Y., Sagayama, H., Berman, E. S. F., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., Blanc, S., Bonomi, A., Bouten, C. V. C., Bovet, P., Buchowski, M. S., Butte, N. F.; Camps, S. G. J. A., Close, G. L., ... Wong, W. W. (2021). A standard calculation methodology for human doubly labeled water studies. Cell Reports Medicine, 2(2): 100203.
dc.identifier.issn2666-3791
dc.identifier.urihttps://hdl.handle.net/11250/2824086
dc.description.abstractThe doubly labeled water (DLW) method measures total energy expenditure (TEE) in free-living subjects. Several equations are used to convert isotopic data into TEE. Using the International Atomic Energy Agency (IAEA) DLW database (5,756 measurements of adults and children), we show considerable variability is introduced by different equations. The estimated rCO2 is sensitive to the dilution space ratio (DSR) of the two isotopes. Based on performance in validation studies, we propose a new equation based on a new estimate of the mean DSR. The DSR is lower at low body masses (<10 kg). Using data for 1,021 babies and infants, we show that the DSR varies non-linearly with body mass between 0 and 10 kg. Using this relationship to predict DSR from weight provides an equation for rCO2 over this size range that agrees well with indirect calorimetry (average difference 0.64%; SD = 12.2%). We propose adoption of these equations in future studies.
dc.language.isoeng
dc.publisherElsevier
dc.rightsNavngivelse 4.0 Internasjonal
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no
dc.titleA standard calculation methodology for human doubly labeled water studies
dc.typeJournal article
dc.typePeer reviewed
dc.description.versionpublishedVersion
dc.rights.holder© 2021 The Author(s)
dc.source.pagenumber14
dc.source.volume2
dc.source.journalCell Reports Medicine
dc.source.issue2
dc.identifier.doihttps://doi.org/10.1016/j.xcrm.2021.100203
dc.identifier.cristin1914145
dc.relation.projectUniversitetet i Agder: 689019
dc.relation.projectUniversitetet i Oslo: 185511330
dc.source.articlenumber100203
cristin.qualitycode1


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