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dc.contributor.authorTarp, Jakob
dc.contributor.authorFagerland, Morten Wang
dc.contributor.authorDalene, Knut Eirik
dc.contributor.authorSteene-Johannessen, Jostein
dc.contributor.authorHansen, Bjørge Hermann
dc.contributor.authorJefferis, Barbara
dc.contributor.authorWhincup, Peter H.
dc.contributor.authorDiaz, Keith M.
dc.contributor.authorHooker, Steven P.
dc.contributor.authorHoward, Virginia J.
dc.contributor.authorChernofsky, Ariel
dc.contributor.authorLarson, Martin G.
dc.contributor.authorSpartano, Nicole
dc.contributor.authorVasan, Ramachandran S.
dc.contributor.authorDohrn, Ing-Mari
dc.contributor.authorHagströmer, Maria
dc.contributor.authorEdwardson, Charlotte
dc.contributor.authorYates, Thomas
dc.contributor.authorShiroma, Eric
dc.contributor.authorDempsey, Paddy C.
dc.contributor.authorWijndaele, Katrien
dc.contributor.authorAnderssen, Sigmund Alfred
dc.contributor.authorLee, I-Min
dc.contributor.authorEkelund, Ulf
dc.date.accessioned2022-02-16T10:09:28Z
dc.date.available2022-02-16T10:09:28Z
dc.date.created2022-01-28T12:36:11Z
dc.date.issued2021
dc.identifier.citationTarp, J., Fagerland, M. W., Dalene, K. E., Steene-Johannessen, J., Hansen, B. H., Jefferis, B., Whincup, P. H., Diaz, K. M., Hooker, S. P., Howard, V. J., Chernofsky, A., Larson, M. G., Spartano, N., Vasan, R. S., Dohrn, I.-M., Hagströmer, M., Edwardson, C., Yates, T., Shiroma, E., Dempsey, P. C., Wijndaele, K., Anderssen, S. A., Lee, I-M. & Ekelund, U. (2021). Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies. British Journal of Sports Medicine.en_US
dc.identifier.issn1473-0480
dc.identifier.urihttps://hdl.handle.net/11250/2979306
dc.description.abstractBackground: The joint associations of total and intensity-specific physical activity with obesity in relation to all-cause mortality risk are unclear. Methods: We included 34 492 adults (72% women, median age 62.1 years, 2034 deaths during follow-up) in a harmonised meta-analysis of eight population-based prospective cohort studies with mean follow-up ranging from 6.0 to 14.5 years. Standard body mass index categories were cross-classified with sample tertiles of device-measured total, light-to-vigorous and moderate-to-vigorous physical activity and sedentary time. In five cohorts with waist circumference available, high and low waist circumference was combined with tertiles of moderate-to-vigorous physical activity. Results: There was an inverse dose–response relationship between higher levels of total and intensity-specific physical activity and mortality risk in those who were normal weight and overweight. In individuals with obesity, the inverse dose–response relationship was only observed for total physical activity. Similarly, lower levels of sedentary time were associated with lower mortality risk in normal weight and overweight individuals but there was no association between sedentary time and risk of mortality in those who were obese. Compared with the obese-low total physical activity reference, the HRs were 0.59 (95% CI 0.44 to 0.79) for normal weight-high total activity and 0.67 (95% CI 0.48 to 0.94) for obese-high total activity. In contrast, normal weight-low total physical activity was associated with a higher risk of mortality compared with the obese-low total physical activity reference (1.28; 95% CI 0.99 to 1.67). Conclusions: Higher levels of physical activity were associated with lower risk of mortality irrespective of weight status. Compared with obesity-low physical activity, there was no survival benefit of being normal weight if physical activity levels were low.en_US
dc.language.isoengen_US
dc.publisherBMJ Publishing Groupen_US
dc.rightsNavngivelse-Ikkekommersiell 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/deed.no*
dc.titleDevice-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studiesen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© 2021 The Author(s)en_US
dc.subject.nsiVDP::Medisinske Fag: 700::Helsefag: 800en_US
dc.subject.nsiVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850en_US
dc.source.journalBritish Journal of Sports Medicineen_US
dc.identifier.doi10.1136/bjsports-2021-104827
dc.identifier.cristin1992308
cristin.qualitycode2


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Navngivelse-Ikkekommersiell 4.0 Internasjonal
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