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dc.contributor.authorBjørke, Ann Christin Helgesen
dc.contributor.authorSweegers, Maike G.
dc.contributor.authorBuffart, Laurien M.
dc.contributor.authorRaastad, Truls
dc.contributor.authorNygren, Peter
dc.contributor.authorBerntsen, Sveinung
dc.date.accessioned2020-03-16T21:28:51Z
dc.date.available2020-03-16T21:28:51Z
dc.date.created2019-10-01T12:43:24Z
dc.date.issued2019
dc.identifier.citationBjørke, A. C. H., Sweegers, M. G., Buffart, L. M., Raastad, T., Nygren, P. & Berntsen, S. (2019). Which exercise prescriptions optimize V̇O2max during cancer treatment? – A systematic review and meta‐analysis. Scandinavian Journal of Medicine & Science in Sports, 29(9), 1274-1287. doi:en_US
dc.identifier.issn1600-0838
dc.identifier.urihttps://hdl.handle.net/11250/2647067
dc.descriptionAuthor's accepted version (post-print).en_US
dc.descriptionThis is the peer reviewed version of the following article: Bjørke, A. C. H., Sweegers, M. G., Buffart, L. M., Raastad, T., Nygren, P. & Berntsen, S. (2019). Which exercise prescriptions optimize V̇O2max during cancer treatment? – A systematic review and meta‐analysis. Scandinavian Journal of Medicine & Science in Sports, 29(9), 1274-1287, which has been published in final form at https://doi.org/10.1111/sms.13442. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
dc.descriptionAvailable from 30/04/2020.
dc.description.abstractThe aims of the present systematic review and meta‐analysis were to investigate the effect of exercise on maximal oxygen uptake (VO2max) and to investigate whether exercise frequency, intensity, duration, and volume are associated with changes in VO2max among adult patients with cancer undergoing treatment. Medline and Embase through OvidSP were searched to identify randomized controlled trials. Two reviewers extracted data and assessed the risk of bias. The overall effect size and differences in effects for different intensities and frequencies were calculated on change scores and post‐intervention VO2max data, and the meta‐regression of exercise duration and volumes was analyzed using the Comprehensive Meta‐Analysis software. Fourteen randomized controlled trials were included in the systematic review, comprising 1332 patients with various cancer types receiving (neo‐)adjuvant chemo‐, radio‐, and/or hormone therapy. Exercise induced beneficial changes in VO2max compared to usual care (effect size = 0.46, 95% Confidence Interval = 0.23‐0.69). Longer session duration (P = 0.020), and weekly duration (P = 0.010), larger weekly volume (P < 0.001), and shorter intervention duration (P = 0.005) were significantly associated with more beneficial changes in VO2max. No differences in effects between subgroups with respect to frequency and intensity were found. In conclusion, exercise has beneficial effects on VO2max in patients with cancer undergoing (neo‐)adjuvant treatment. As interventions with larger exercise volumes and longer session durations resulted in larger beneficial changes in VO2max, exercise frequency, intensity, and duration should be considered carefully for sufficient exercise volume to induce changes in VO2max for this patient group.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.titleWhich exercise prescriptions optimize V̇O2max during cancer treatment?—A systematic review and meta‐analysisen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionacceptedVersionen_US
dc.subject.nsiVDP::Samfunnsvitenskap: 200::Samfunnsvitenskapelige idrettsfag: 330en_US
dc.source.pagenumber1274-1287en_US
dc.source.volume29en_US
dc.source.journalScandinavian Journal of Medicine & Science in Sportsen_US
dc.source.issue9en_US
dc.identifier.doi10.1111/sms.13442
dc.identifier.cristin1732338
cristin.qualitycode2


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